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Updated: Jan 31, 2026

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
Published on: April 18, 2025
[Current trends in bladder cancer diagnosis].
A I Glukhov1,2,3,4, N V Polotdykova1,2,3,4, S A Gordeev1,2,3,4
1I.M. Sechenov First Moscow State Medical University of Minzdrav of Russia, Moscow, Russia.
Bladder cancer recurrence rates can reach 80%, necessitating improved early detection methods. Non-invasive diagnostic tools are being developed to reduce cystoscopies and establish a new standard for bladder cancer diagnosis.
Area of Science:
- Oncology
- Urology
- Medical Diagnostics
Background:
- Bladder cancer constitutes 2.8% of all malignant tumors in the Russian Federation.
- It is the second most common genitourinary cancer after prostate cancer.
- Non-muscle invasive bladder cancer has a high recurrence rate, potentially reaching 80%.
Purpose of the Study:
- To highlight the critical issue of non-muscle invasive bladder cancer recurrence.
- To emphasize the global focus on developing reliable early detection methods.
- To explore the potential of non-invasive diagnostics as a "golden" standard.
Main Methods:
- Review of current research on bladder cancer detection.
- Analysis of recurrence rates for non-muscle invasive bladder cancer.
- Discussion of advancements in non-invasive diagnostic technologies.
Main Results:
- High recurrence rates underscore the need for better monitoring.
- Significant global attention is directed towards early and non-invasive detection strategies.
- Non-invasive methods show promise in reducing the need for cystoscopies.
Conclusions:
- Developing reliable, non-invasive early detection methods for bladder cancer is crucial.
- These advancements could potentially lower the frequency of cystoscopies.
- Non-invasive diagnostics may become the new standard for bladder cancer detection.
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