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Updated: Jan 31, 2026

Retzius-Sparing Robot-Assisted Radical Prostatectomy
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Radical Prostatectomy or Watchful Waiting in Prostate Cancer - 29-Year Follow-up

Anna Bill-Axelson1, Lars Holmberg1, Hans Garmo1

  • 1From the Department of Surgical Sciences (A.B.-A., L.H., M.H.), Regional Cancer Center Uppsala Örebro (H.G.), and the Department of Pathology (C.B.), Uppsala University Hospital, Uppsala, the School of Health and Medical Sciences, Örebro University, and the Department of Urology, Örebro University Hospital, Örebro (S.-O.A., O.A., J.-E.J.), the Department of Medical Epidemiology and Biostatistics (H.-O.A.), Karolinska Institutet, Stockholm, and the Division of Clinical Cancer Epidemiology, Sahlgrenska Academy, Gothenburg (G.S.) - all in Sweden; the School of Medicine, Division of Cancer Studies (L.H., H.G.), and the School of Cancer and Pharmaceutical Sciences (L.H.), King's College London, London; the Department of Urology, Helsinki University Hospital (K.T.), and the Department of Pathology, University of Helsinki (S.N.), Helsinki; the Department of Epidemiology, Harvard T.C. Chan School of Public Health, Boston (H.-O.A.); and the Clinical Effectiveness Research Group, Institute of Health and Society, University of Oslo, Oslo (H.-O.A.).

The New England Journal of Medicine
|December 22, 2018
PubMed
Summary

Radical prostatectomy significantly reduces prostate cancer mortality and extends life expectancy by nearly 3 years for men with localized disease. High Gleason scores and extracapsular extension predict a worse prognosis.

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