Outcomes of Renal Allograft Recipients With Hepatitis B From January 2000 to December 2010

The author evaluated graft and patient outcomes of renal allograft recipients with hepatitis B infection at National Kidney and Transplant Institute from January 2000 to December 2010.

Retrospective study with patients who underwent renal transplant with HBV infection and group of HBV-negative patients in the same post-transplantation period. Data were gathered from the patients' in-hospital and out-patient clinic records and the MEDSYS database.

A total of 38 renal transplant recipients were followed up. Hepatitis B cases had a 410% increased risk of having graft failure compared to hepatitis B-negative patients. The mean duration of graft survival was 145.26 (±60.40) months (12 years) in HBV negative compared to 134.29 (±67.94) months (11 years) in HBV-positive post-transplant patients. There was no difference between hepatitis B-positive and B-negative groups in terms of patient survival. The mean duration of patient survival was 156.97 (±60.62) months (13 years) in HBV negative compared to 157.37 (±61.09) months (13 years) in HBV positive post-transplant patients. There was also no significant difference in the mean values of the glomerular filtration rate and level of proteinuria between the two groups.

Although patient survival was similar in both groups, there was increased risk of graft failure in hepatitis B-positive patients.