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Related Concept Videos

Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

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Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
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Related Experiment Video

Updated: Jan 31, 2026

Eye Irritation Test EIT for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial RhCE Tissue Model
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Probing the Irritability-Suicidality Nexus.

Argyris Stringaris1, Pablo Vidal-Ribas1

  • 1Mood Brain & Development Unit, Emotion and Development Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD.

Journal of the American Academy of Child and Adolescent Psychiatry
|December 23, 2018
PubMed
Summary
This summary is machine-generated.

Suicide is a critical public health issue, especially among adolescents. This study investigates childhood irritability trajectories as potential early predictors of adolescent suicidality, aiming to identify modifiable risk factors.

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Area of Science:

  • Child and Adolescent Psychiatry
  • Mental Health Research
  • Public Health

Background:

  • Suicide is a leading cause of death in adolescents, with suicidality as a significant risk factor.
  • Identifying modifiable early predictors of suicidality is crucial for mental health research.
  • Childhood irritability is a common symptom across youth psychiatric disorders.

Discussion:

  • This study explores the link between distinct childhood irritability trajectories and adolescent suicidality.
  • Understanding these developmental pathways can inform early intervention strategies.
  • Irritability in childhood may represent a critical period for developing interventions targeting suicidality.

Key Insights:

  • Distinct childhood irritability trajectories are associated with adolescent suicidality.
  • Early identification of irritability patterns may help predict suicide risk.
  • This research highlights irritability as a potential target for suicide prevention in youth.

Outlook:

  • Further research can refine understanding of irritability's role in adolescent suicidality.
  • Findings may lead to the development of novel, targeted interventions for youth at risk.
  • Longitudinal studies are needed to confirm these associations and evaluate interventions.