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Laboratory guidelines for the diagnosis of patients with cryoglobulinaemic syndrome
A Mariscal-Rodríguez1, L M Villar Guimerans2, M López-Trascasa3
1Servicio de Inmunología, Hospital de la Santa Creu i, Sant Pau, Barcelona, España.
Abstract:
Cryoglobulinaemic syndromes include a collection of manifestations that are found in various diseases and that share a pathophysiological mechanism: cryoglobulin deposit in vascular beds. For these syndromes, the presence of cryoglobulins is a diagnostic criterion, and their correct detection and characterisation are therefore essential. The Immunochemistry Group of the Spanish Society of Immunology conducted a comprehensive clinical and methodological review, due to the interlaboratory heterogeneity in techniques, with the objective of providing a useful and effective tool for diagnosing cryoglobulinaemic syndromes.
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