Study of aggressive carcinomas through orbital metastasis

Area of Science:

• Ophthalmology
• Oncology
• Radiology

Background:

• Orbital metastasis is an uncommon condition.
• It presents with diverse clinical symptoms, including vision loss and double vision.
• Prognosis is generally unfavorable.

Purpose of the Study:

• To present two clinical cases of orbital metastasis.
• To highlight the diagnostic challenges and varied presentations.
• To emphasize the importance of considering orbital metastasis in at-risk patients.

Main Methods:

• Case report analysis of two patients with orbital metastasis.
• Utilized neuroimaging (MRI/CT) for tumor characterization and extent.
• Systemic and anatomo-pathological studies for primary tumor diagnosis.

Main Results:

• Case 1: 63-year-old male with small cell lung cancer metastasized to the orbit, causing vision loss and diplopia with bone invasion.
• Case 2: 69-year-old female with early-stage breast cancer metastasized to orbital muscles, causing motility issues and proptosis.
• Confirmed orbital metastasis via anatomo-pathological examination in both cases.

Conclusions:

• Orbital metastasis requires a high index of suspicion in patients with known cancer or risk factors.
• Advanced imaging techniques are essential for diagnosis and staging.
• Prompt diagnosis and management are critical due to the unfavorable prognosis.