Jejunal leiomyosarcoma: Report of a rare case diagnosed on cytology

Jejunal leiomyosarcomas (LMS) are extremely rare. Of all the mesenchymal tumors of the small intestine, Gastrointestinal Stromal Tumors (GIST) comprise the majority. LMS of the small intestine have been documented as isolated reports or only a very small percentage of the smooth muscle tumors of the small intestine. Furthermore, cytological evaluation and preoperative diagnosis of small intestinal LMS is not well documented, even though cytology of small intestinal GISTs has been studied. Since preoperative diagnosis is useful in differentiating benign from malignant lesions, correctly staging malignant lesions and identifying the plan of management, preoperative cytological evaluation assumes a great significance. We report a case of jejunal leiomyosarcoma diagnosed on cytology. KEY MESSAGES: Although extremely rare, small intestinal LMS should be considered in the differential diagnosis of small intestinal mesenchymal lesions. FNAC, with preparation of cell block, and subsequent IHC can help in the preoperative diagnosis and formulating a plan of management of the patients.