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Ion-pair approach coupled with nanoparticle formation to increase bioavailability of a low permeability charged drug

Isabel Lozoya-Agullo1, Marcos Planelles2, Matilde Merino-Sanjuán3

  • 1Department of Pharmacokinetics and Pharmaceutical Technology, Miguel Hernandez University, San Juan de Alicante, 03550 Alicante, Spain; Department of Pharmacokinetics and Pharmaceutical Technology, University of Valencia, Av. de Blasco Ibáñez, 13, 46010 Valencia, Spain.

International Journal of Pharmaceutics
|December 23, 2018
PubMed

Keywords:
BioavailabilityCharged drugsIon-pairLow permeability drugNanoparticlesPLGA

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