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Olfactory and cognitive functions in Chinese individuals at clinical high risk for psychosis
Ying He1, Zongchang Li2, Xiaoqian Ma2
1Department of Psychiatry, The Second Xiangya Hospital of Central South University, Renmin Road 139, Changsha, Hunan 410011, China; Center for Behavioral Genomics, Department of Psychiatry, Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA.
Abstract:
The abnormal olfactory function has been regarded as a sign in psychosis. To confirm the theory that olfactory and cognitive functions are deficient in Chinese cohort with clinical high risk state of psychosis, 19 individuals at clinical high risk for psychosis (CHRs) and 37 healthy controls (HCs) were recruited. The CHRs scored significantly lower than the HCs in the olfactory identification test and all other cognitive tests. Our findings suggest that olfactory dysfunction may be an early change of psychosis.
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