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Published on: May 27, 2015
A new flavanone glycoside isolated from Tournefortia sibirica
Shengbao Diao1, Mei Jin2, Chun Shi Jin1
1a Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, Yanbian University College of Pharmacy , Yanji , China.
Abstract:
A new flavanone glycoside, (2S)-dihydrooroxylin A 7-O-[β-D-apiosyl(12)]-β-D-glucoside (1), and four known compounds (2-5) were isolated from Tournefortia sibirica L. The chemical structures of these compounds were determined by 1 D and 2 D NMR and HR-ESI-MS spectra, and results were compared with data from the literature. These five compounds (1-5) were isolated from the family Boraginaceae for the first time. Anti-inflammatory effects of compounds (1-5) were evaluated in terms of inhibition of production of NO, TNF-α, and IL-6 in LPS-induced RAW 264.7 cells.
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