Related Experiment Video
Updated: Jan 31, 2026
06:11
An Efficient Method to Obtain Dedifferentiated Fat Cells
Published on: July 15, 2016
8.4K
Proliferative Funiculitis-Like Dedifferentiated Liposarcoma With Mesothelial Glandular Structures: A Diagnostic
Alexey S Konstantinov1,2, Ksenya V Shelekhova1,2
11 Clinical Research and Practical Center for Specialized Oncological Care, Saint Petersburg, Russia.
International Journal of Surgical Pathology
|December 25, 2018
Summary
Dedifferentiated liposarcoma can mimic other conditions. This case highlights a rare spermatic cord dedifferentiated liposarcoma initially misdiagnosed as pseudosarcomatous proliferative funiculitis.
Area of Science:
- Oncology
- Pathology
Background:
- Dedifferentiated liposarcoma is a malignant mesenchymal neoplasm characterized by a wide range of histological appearances.
- Liposarcomas are malignant tumors arising from adipose tissue, with dedifferentiated liposarcoma representing an aggressive subtype.
Observation:
- A 66-year-old male presented with a mass in the spermatic cord.
- Initial histopathological examination led to a misdiagnosis of pseudosarcomatous proliferative funiculitis with mesothelial proliferation.
Findings:
- The re-evaluation confirmed the diagnosis of dedifferentiated liposarcoma of the spermatic cord.
- This highlights the potential for diagnostic challenges in differentiating dedifferentiated liposarcoma from benign mimics.
Implications:
- Accurate diagnosis is crucial for appropriate patient management and treatment planning.
- Increased awareness of the morphological spectrum of dedifferentiated liposarcoma is necessary for pathologists.
Keywords:
mesothelial structuresparatesticular liposarcomapseudosarcomatous proliferative funiculitisMore Related Videos
Related Concept Videos
01:20Proliferative Phase
1.4K
The proliferative phase typically occurs after menstruation and lasts between 6 to 13 days in a standard 28-day cycle. This phase involves the reconstruction of the endometrium, guided by estrogen produced by the developing ovarian follicle.
Notably, the stratum basale, the basal layer of the endometrium, including the basal parts of the uterine glands, remains unaffected by menstruation. Stem cells in this layer undergo mitosis, regenerating the stratum functionalis and thickening the...
Notably, the stratum basale, the basal layer of the endometrium, including the basal parts of the uterine glands, remains unaffected by menstruation. Stem cells in this layer undergo mitosis, regenerating the stratum functionalis and thickening the...
1.4K
01:20Classification of Epithelial Tissues: Glandular Epithelium
11.9K
The glandular epithelium is made of one or more epithelial cells modified to synthesize and secrete chemical substances. Glandular epithelia can be classified based on cell number. Unicellular glands have individual secretory cells scattered across the epithelial monolayer. In contrast, multicellular glands consist of a hollow tubular duct attached to the cluster of secretory cells located in the deep pockets.
Multicellular glands are formed during early development when epithelial budding...
Multicellular glands are formed during early development when epithelial budding...
11.9K
01:22Drug Excretion: Pulmonary and Glandular Routes
708
Gaseous substances like general anesthetics are absorbed and excreted through the lungs via simple diffusion. This process depends on factors such as pulmonary blood flow, respiration rate, and the substance's solubility. Gaseous anesthetics like nitrous oxide with low blood solubility are excreted rapidly, while compounds like alcohol, with high blood and tissue solubility, are excreted slowly.
Drugs can also be excreted in breast milk, which is crucial for breastfeeding infants. The...
Drugs can also be excreted in breast milk, which is crucial for breastfeeding infants. The...
708
01:29Appendicitis-II: Diagnostic Studies and Management
568
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
568
01:15Myasthenia Gravis: Diagnostic Tests
2.5K
Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
2.5K
01:30Asthma-IV: Diagnostic and Management
3.1K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.1K