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Updated: Jan 31, 2026

A Rehabilitation Program of Exoskeleton-assisted Body Weight-Supported Treadmill Training with Non-immersive Virtual Reality for Stroke Patients
Published on: May 16, 2025
Mirror therapy and treadmill training for patients with chronic stroke: a pilot randomized controlled trial
P Broderick1, F Horgan2, C Blake3
1a School of Science , Institute of Technology Sligo , Sligo , Ireland.
Mirror therapy combined with treadmill training significantly reduced ankle muscle tone in chronic stroke patients. This intervention showed promise for lower-limb recovery compared to placebo, though other functional measures were not significantly different.
Area of Science:
- Neurorehabilitation
- Physical Therapy
- Stroke Recovery
Background:
- Previous lower-limb mirror therapy research primarily utilized non-weight-bearing interventions.
- This study explores a novel combination of mirror therapy and treadmill training for post-stroke lower-limb recovery.
Purpose of the Study:
- To investigate the effect and feasibility of combined mirror therapy and treadmill training.
- To compare this intervention against a placebo in patients with chronic stroke.
Main Methods:
- Thirty patients with chronic stroke participated in a 4-week program.
- Intervention group (n=15) received mirror therapy with treadmill training.
- Placebo group (n=15) received treadmill training without mirror visual feedback.
Main Results:
- A significant reduction in ankle muscle tone (Modified Ashworth Scale) was observed in the mirror therapy group post-training.
- No significant differences were found between groups for walking tests (10MWT, 6MWT) or overall lower extremity function (FMA-LE).
- Muscle tone improvements were not sustained at the 3-month follow-up.
Conclusions:
- Combined mirror therapy and treadmill training effectively reduced ankle muscle tone in chronic stroke survivors.
- The intervention demonstrated feasibility with good participant compliance and no reported adverse events.
- Further research is needed to explore long-term effects and broader functional improvements.
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