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Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Upper Gastrointestinal Bleeding in Chronic Kidney Disease Patients
D Marinescu1, M Lazar2, S Zaharie3
1University of Medicine and Pharmacy of Craiova.
Insights
Patients with chronic kidney disease (CKD) face a high risk of upper gastrointestinal bleeding. However, conservative treatments are highly effective, often negating the need for invasive procedures.
Area of Science:
- Nephrology
- Gastroenterology
Background:
- Chronic kidney disease (CKD) patients exhibit a heightened risk for upper gastrointestinal (GI) bleeding compared to the general population.
- Comorbidities, particularly cardiovascular diseases, are prevalent among CKD patients experiencing GI bleeding.
Observation:
- A study reviewed 30 CKD patients with upper GI bleeding over five years.
- The majority of patients (53.3%) were on hemodialysis; none were on peritoneal dialysis.
- A low percentage (10%) were on oral anticoagulant therapy before the bleeding event.
Findings:
- Conservative management proved successful for all patients.
- No cases required endoscopic or surgical intervention for hemostasis.
Implications:
- Conservative treatment strategies demonstrate high efficacy in managing upper GI bleeding in CKD patients.
- These findings suggest a potential shift in management protocols, prioritizing conservative measures.
Abstract:
Aim: To investigate upper GI bleeding as a particular complication in chronic kidney disease patients. Material and methhod: 30 chronic kidney disease patients admitted to the Nephrology Department for upper gastrointestinal bleeding over a period of 5 years. Results: 16 patients were undergoing hemodialysis (53.3%) and 14 patients were not in a hemodialysis program. There were no patients undergoing peritoneal dialysis. Very high comorbidity rate for all patients, most important being cardiovascular diseases. Only 10% of patients had oral anticoagulant treatment prior to GI bleeding. Conservative treatment was successful for all patients; no endoscopic or surgical haemostasis was needed. Conclusion: Although chronic disease kidney patients have a high risk of upper GI bleeding compared to the general population, the conservative treatment applied has a very high rate of success in stopping the bleeding without the need for endoscopic or surgical haemostasis treatment.
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