Pattern and Frequency of Short Stature in Albanian Children

A Gjikopulli1, L Grimci1, L Kollcaku1

  • 1Division of Pediatric Endocrinology, Department of Pediatrics, University Hospital Centre "Mother Teresa", Albania.

Insights

A study in Albania found that 46% of children with short stature had an underlying medical condition. Early growth monitoring is crucial for timely diagnosis and intervention in pediatric short stature.

Area of Science:

  • Pediatric Endocrinology
  • Growth and Development
  • Medical Diagnostics

Background:

  • Short stature is defined as height more than 2 standard deviations below the mean for age and sex.
  • While numerous medical conditions can cause poor growth, most short children are otherwise healthy.
  • Identifying the cause of short stature is essential for appropriate management.

Purpose of the Study:

  • To identify and analyze the causes of short stature in Albanian children.
  • To evaluate factors contributing to growth failure in a pediatric population.

Main Methods:

  • Study included 564 children with short stature or slow growth velocity (<-2 z-score).
  • Evaluations involved anthropometric measurements, biochemical and hormonal analyses, radiological studies, and provocative tests.
  • Statistical analysis was performed using Epi-Info CDC 2000 and SPSS.

Main Results:

  • The study analyzed 564 children aged 0.65-18.74 years.
  • Constitutional short stature (37.4%) and growth hormone (GH) deficit (27.5%) were the most frequent diagnoses.
  • Other diagnoses included genetic syndromes (11.9%), familial short stature (6.7%), and idiopathic short stature (5.5%).

Conclusions:

  • A significant proportion (46%) of children evaluated had a pathological cause for their growth failure.
  • This highlights the necessity for vigilant growth monitoring and prompt specialist referral.
  • Delayed evaluation suggests suboptimal growth surveillance in Albania.
Abstract

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