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Long-Term Memory01:18

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Long-term memory is a relatively permanent type of memory, capable of storing vast amounts of information over extended periods. Its storage capacity is generally considered unlimited.
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Updated: Jan 31, 2026

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
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Short-term interval aerobic exercise training does not improve memory functioning in relapsing-remitting multiple

Lisa Baquet1, Helge Hasselmann2, Stefan Patra3

  • 1Institute for Neuroimmunology and Multiple Sclerosis (INIMS), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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|December 25, 2018
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Summary

Aerobic exercise did not improve cognition in relapsing-remitting multiple sclerosis (RRMS) patients. This study found no significant benefits for cognitive function, quality of life, or fatigue levels.

Keywords:
Aerobic exercise trainingCognitionMemory functionMultiple sclerosisNeuroimmunologyNeurorehabilitation

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Area of Science:

  • Neurology
  • Exercise Science
  • Rehabilitation Medicine

Background:

  • Limited research exists on aerobic exercise interventions for cognitive function in multiple sclerosis (MS).
  • Cognitive impairment is a significant challenge for individuals with MS, impacting daily life.

Purpose of the Study:

  • To investigate the effects of a 12-week aerobic exercise program on cognitive function in relapsing-remitting multiple sclerosis (RRMS).
  • To assess the impact of exercise on verbal learning, quality of life, fatigue, and depressive symptoms.

Main Methods:

  • A randomized controlled trial involving 68 RRMS patients (34 intervention, 34 control).
  • The intervention group engaged in tailored aerobic exercise 2-3 times weekly for 12 weeks.
  • Cognitive function was primarily assessed using the Verbal Learning and Memory Test (VLMT).

Main Results:

  • No significant improvements were observed in the primary endpoint (VLMT) or other cognitive measures.
  • Aerobic exercise did not yield significant benefits for quality of life, fatigue, or depressive symptoms.
  • The study included 68% females, with a mean age of 39 and a mean disease duration of 6.3 years.

Conclusions:

  • This study did not demonstrate that aerobic exercise improves cognitive function in individuals with RRMS.
  • Further research may be needed to explore optimal exercise strategies or other interventions for cognitive deficits in MS.