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Percutaneous Pulmonary Valve Implantation: Current Status and Future Perspectives
Bart W Driesen1,2, Evangeline G Warmerdam1, Gert-Jan Sieswerda1
1Department of Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.
Current Cardiology Reviews
|December 25, 2018
Summary
Congenital heart disease patients often need multiple pulmonary valve replacements. Percutaneous pulmonary valve implantation (PPVI) is a safe option, but anatomical variations can affect success. This review covers PPVI status and future outlook.
Area of Science:
- Cardiology
- Interventional Cardiology
- Congenital Heart Disease
Background:
- Congenital heart disease (CHD) frequently involves right ventricle outflow tract (RVOT) dysfunction.
- Patients often require lifelong, sequential pulmonary valve replacements.
- Percutaneous pulmonary valve implantation (PPVI) emerged in 2000 as an alternative.
Purpose of the Study:
- To review the current status of percutaneous pulmonary valve implantation (PPVI).
- To discuss the future perspectives and challenges of PPVI in managing RVOT dysfunction.
- To highlight the impact of anatomical variations on PPVI success.
Main Methods:
- Literature review of PPVI procedures and outcomes worldwide.
- Analysis of PPVI safety and efficacy data since 2000.
- Discussion of anatomical factors influencing procedural success.
Main Results:
- Over 10,000 PPVI procedures have been performed globally.
- PPVI has demonstrated overall safety and effectiveness in managing RVOT dysfunction.
- Certain patient anatomical variations present limitations to successful PPVI.
Conclusions:
- PPVI is a valuable, established treatment for RVOT dysfunction in CHD.
- Addressing anatomical challenges is crucial for optimizing future PPVI outcomes.
- Continued research and technological advancements are needed to expand PPVI's applicability.
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