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Updated: Jan 31, 2026

Integration of Miniaturized Solid Phase Extraction and LC-MS/MS Detection of 3-Nitrotyrosine in Human Urine for Clinical Applications
Published on: July 14, 2017
Solid Phase Microextraction: Apparatus, Sorbent Materials, and Application
Muhammad Sajid1, Mazen Khaled Nazal1, Małgorzata Rutkowska2
1a Center for Environment and Water , Research Institute King Fahd University of Petroleum and Minerals , Dhahran , Saudi Arabia.
Abstract:
The primary objective of this review article is to strategically screen and highlight the advancements in the area of solid phase microextraction (SPME). The plenty of review articles have been written on different aspects of SPME, this review is dedicated to provide the brief but clear overview of the research footprints so produced from SPME. Some of the key advancements in types and designs, coating materials, coating strategies, in vivo sampling and direct coupling of SPME with MS have been critically discussed.
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