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The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
23:33

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation

Published on: February 28, 2012

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Left atrial appendage occlusion using LAmbre Amulet and Watchman in atrial fibrillation

Shaojie Chen1, K R Julian Chun1, Stefano Bordignon1

  • 1Frankfurt Academy For Arrhythmias (FAFA), Cardioangiologisches Centrum Bethanien (CCB) Frankfurt am Main, Medizinische Klinik III, Agaplesion Markus Krankenhaus, Frankfurt am Main, Germany.

Journal of Cardiology
|December 26, 2018
PubMed

Insights

Left atrial appendage closure devices like LAmbre, Amulet, and Watchman show high implant success and good short-term outcomes for non-valvular atrial fibrillation patients.

Area of Science:

  • Cardiology
  • Medical Devices
  • Interventional Cardiology

Background:

  • Left atrial appendage closure (LAAC) is an alternative to anticoagulation for non-valvular atrial fibrillation (AF).
  • Comparison of LAAC devices is crucial for clinical decision-making.
  • Evaluating peri-procedural and short-term outcomes of different LAAC systems is essential.

Purpose of the Study:

  • To compare the LAmbre LAAC system with the Amulet and Watchman devices.
  • To assess peri-procedural and short-term clinical outcomes.
  • To evaluate implant success rates and adverse events.

Main Methods:

  • Prospective observational study.
  • 140 patients with non-valvular atrial fibrillation were enrolled.
  • Comparison of LAmbre (n=30), Amulet (n=74), and Watchman (n=36) devices.

Main Results:

  • High implant success rates: 100% for LAmbre, 99% for Amulet, 100% for Watchman.
  • No significant differences in device repositions, fluoroscopic/procedural times, or major peri-procedural adverse events.
  • Good device stability and clinical condition at six months' follow-up.

Conclusions:

  • LAmbre, Amulet, and Watchman demonstrate comparable safety and efficacy.
  • These LAAC devices offer a favorable risk-benefit profile for AF patients.
  • Further research may explore long-term outcomes and specific patient populations.
Abstract

Keywords:
Atrial fibrillationCardiac catheterLeft atrial appendage closurePreventionStroke

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