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Updated: Jan 31, 2026

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
Published on: August 15, 2022
Conceptual Issues in DCDD Donor Death Determination.
Organ donors declared dead using circulatory determination of death (DCDD) are a subject of debate. The controversy hinges on distinguishing permanent versus irreversible cessation of vital functions, crucial for defining death.
Area of Science:
- Medical Ethics
- Physiology
- Organ Donation
Background:
- Organ donation after circulatory determination of death (DCDD) programs are widely used.
- A persistent ethical and medical debate exists regarding the precise moment of death declaration in DCDD.
- The controversy centers on whether circulatory and respiratory arrest, once declared, signifies irreversible death.
Purpose of the Study:
- To clarify the disagreement surrounding the definition of death in organ donors.
- To distinguish between permanent and irreversible cessation of vital functions.
- To reconcile the medical practice standard with the biological concept of death.
Main Methods:
- Analysis of the distinction between permanent and irreversible cessation of circulation and respiration.
- Examination of the difference between the medical practice standard for death declaration and the biological definition of death.
- Conceptual clarification of the criteria for declaring death in organ donors.
Main Results:
- The disagreement stems from conflating permanent cessation of vital functions with irreversible cessation.
- The medical practice standard declares death based on permanent cessation.
- The biological concept of death requires irreversible cessation.
Conclusions:
- Distinguishing between permanent and irreversible cessation of vital functions is key to resolving the DCDD death declaration debate.
- Death is biologically defined by irreversible cessation, not merely permanent cessation.
- Clarifying these distinctions can improve understanding and practice in organ donation.
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