Flagellin parts acquiring a regular structure during polymerization are disposed on the molecule ends

A S Kostyukova¹, M G Pyatibratov, V V Filimonov

¹Institute of Protein Research, Academy of Sciences of the USSR, Moscow Region.

|December 5, 1988

Abstract:

Flagellins of two Escherichia coli strains have been investigated by limited proteolysis and scanning microcalorimetry. It has been shown that a monomer flagellin consists of two parts: a central one cooperatively melting, rather resistant to proteases, and the other without a stable tertiary structure and thus easily degrading terminals. Just these terminals acquire a regular structure during polymerization. Core fragments of the two strains have been isolated and characterized.

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Abstract:

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