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Medical Device Histology and Pathology: A Horse of a Different Color
Jaime Paulin1, Serge D Rousselle2, Stacey Fossey3
11 Medtronic Physiological Research Laboratories, Minneapolis, Minnesota, USA.
Abstract:
Medical devices comprise a wide variety of therapeutic tools aimed at modulating or restoring organ function. Devices may be implanted or activated temporally or permanently, and are used to deliver a wide range of therapies such as drugs, electrical stimulation, laser, thermal energy, offer mechanical support, and restore sensory functions. Technological advancements allow improvement and development of devices at a rapid pace. This special issue of Toxicologic Pathology addresses a need for more publications focused on pathology evaluation of medical devices in preclinical studies and highlights fundamental approaches through practical examples bringing into perspective the essential role of pathologists in this field.
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