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The Case for Using Hydrogen Peroxide Contact Lens Care Solutions: A Review.

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  • 1Office of the Vice President for Research (J.J.N.), The University of Alabama at Birmingham, Birmingham, AL; School of Optometry (J.J.N.), The University of Alabama at Birmingham, Birmingham, AL; Clinical Trial Consultant (R.L.C.), Atlanta, GA; School of Optometry (K.D.) University of California Berkeley, Berkeley, CA; Clinical Research Scientist and Consultant (K.D.), Berkeley, CA; School of Optometry and Vision Science (L.J.), University of Waterloo, Waterloo, ON, Canada; Centre for Ocular Research & Education (L.J.), University of Waterloo, Waterloo, ON, Canada; Internal Clinics (C.W.L.), The Eye Center, Southern College of Optometry, Memphis, TN; Clinical Development & Medical Affairs, North America (M.M.M.), Alcon, a Novartis Company, Fort Worth, TX; Department of Ophthalmology and Visual Sciences (L.S.-F.), Case Western Reserve University, Cleveland, OH; and Contact Lens Service (L.S.-F.), University Hospitals Eye Institute, Cleveland, OH.

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Hydrogen peroxide (H2O2) lens care systems offer superior disinfection and safety for reusable contact lenses. One-step H2O2 solutions provide better compliance, efficacy, and ocular comfort compared to multipurpose solutions (MPS).

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Area of Science:

  • Ophthalmology
  • Optometry
  • Biomedical Science

Background:

  • Multipurpose solutions (MPS) for reusable contact lenses have drawbacks like preservatives and compliance issues.
  • Hydrogen peroxide (H2O2) lens care systems offer potential advantages over MPS.
  • One-step H2O2 systems aim to mitigate challenges associated with traditional MPS use.

Purpose of the Study:

  • To review the evolution of H2O2 lens care systems.
  • To examine scientific and clinical evidence on H2O2 systems' ease of use, compatibility, efficacy, and safety.
  • To compare H2O2 systems with MPS for reusable contact lens wearers.

Main Methods:

  • Literature review of H2O2 lens care systems.
  • Analysis of scientific and clinical data on H2O2 system performance.
  • Comparative evaluation of H2O2 systems versus MPS.

Main Results:

  • One-step H2O2 systems demonstrate favorable compliance and efficacy.
  • H2O2 systems show good lens and tissue compatibility.
  • Ocular surface safety and comfort are generally improved with H2O2 systems compared to MPS.

Conclusions:

  • One-step H2O2 systems offer advantages in compliance, efficacy, comfort, and ocular surface outcomes.
  • H2O2 systems are a viable alternative to MPS for most reusable contact lens wearers.
  • Eye care practitioners should consider recommending one-step H2O2 systems as a first-line option.