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The STRAND Chart: A survival time control chart
1MRC Biostatistics Unit, University of Cambridge, Cambridge, UK.
Abstract:
The STRAND Chart (Survival Time, Risk-Adjusted, N-Division Chart) is a new tool for online risk-adjusted (RA) monitoring of survival outcomes. The chart is drawn in continuous time, making it responsive to change in the process of interest, for example, performance over time of a surgical unit and the procedures that they employ. Though it is difficult to achieve with charts designed for the purpose described, we show that our suggested chart keeps patient ordering intact. We discuss the difficulties maintaining patient ordering poses, making reference to other charts in the literature. Our conclusion is that the best approach to preserving patient ordering on any chart of this nature involves compromising on the fullness of presentation of the recorded data. The chart is divided into N strands, each strand relating to a benchmark patient's survival information at tn days following treatment, n = 1,2,…,N. We present a simple version of the chart where the strands consist of Bernoulli RA exponentially weighted moving averages, recording RA failure rates at tn days. It can detect recent process change and historical change. We illustrate the STRAND Chart using a well-known UK post cardiac surgery survival dataset, where the nature of a certain cluster in the data can be seen.
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