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Published on: March 10, 2016
Vitamin D Deficiency as a Factor Influencing Asthma Control in Children
A T Kaaviyaa1, Vidya Krishna1, T S Arunprasath1
1Department of Pediatrics, Sri Ramachandra Medical College and Research Institute, Chennai, India.
Insights
Vitamin D deficiency is linked to poorer asthma control in children. Maintaining adequate vitamin D levels may support better management of persistent asthma.
Area of Science:
- Pediatric Pulmonology
- Nutritional Biochemistry
Background:
- Asthma control is crucial for children's quality of life.
- Vitamin D's role in immune function suggests a potential link to respiratory health.
Purpose of the Study:
- To investigate the association between serum 25-hydroxy vitamin D levels and asthma control in children with moderate persistent asthma.
- To determine if vitamin D status influences asthma control outcomes in pediatric patients on preventer therapy.
Main Methods:
- A study involving 50 children aged 6-18 years with moderate persistent asthma on preventer therapy for at least two months.
- Asthma control was assessed using GINA guidelines (good, partial, or poor).
- Serum 25(OH) Vitamin D levels were measured and correlated with asthma control categories.
Main Results:
- Out of 50 children, 30 had vitamin D deficiency and 18 had insufficient levels.
- Children with vitamin D deficiency showed significantly poorer asthma control (13.3% well-controlled) compared to those with insufficient or sufficient levels (88.9% and 100% well-controlled, respectively).
Conclusions:
- Vitamin D deficiency is significantly associated with suboptimal asthma control in children.
- These findings highlight the importance of assessing and potentially correcting vitamin D status in pediatric asthma management.
Objective:
To study the association between asthma control and serum 25OH Vitamin D levels in children with moderate persistent asthma on preventer therapy.
Methods:
Children aged 6-18 years, with moderate persistent asthma, on preventer therapy for ≥2 months were included. Control was categorized as good, partial or poor as per GINA guidelines. Serum 25 (OH) Vitamin D levels were measured and their relationship with the level of control was studied.
Results:
Out of 50 children enrolled, 22 had well-controlled asthma, and 21 had partially controlled asthma. Vitamin D was deficient in 30 children and insufficient in 18 children. Children with vitamin D deficiency had significantly less well-controlled asthma as compared to those with insufficient or sufficient levels of 25 (OH) vitamin D (13.3% vs 88.9% vs 100%).
Conclusions:
Vitamin D deficiency is associated with suboptimal asthma control.
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