Association of Vitamin D Deficiency with Chronic Stable Angina: A Case Control Study

Area of Science:

• Cardiology
• Endocrinology
• Nutritional Science

Background:

• Coronary heart disease represents a significant global health burden.
• Vitamin D deficiency is a potential, modifiable risk factor for ischemic heart diseases.
• The precise link between vitamin D levels and cardiovascular health requires further investigation.

Purpose of the Study:

• To compare vitamin D status in patients with chronic stable angina versus a control group.
• To investigate the association between vitamin D levels and chronic stable angina.

Main Methods:

• A case-control study involving 42 adult patients with chronic stable angina and 42 matched controls.
• Data collection included medical history, physical examination, and laboratory tests for vitamin D, lipid profile, and blood sugar.
• Participants were recruited from family medicine and internal medicine clinics at Cairo University Hospitals.

Main Results:

• A high prevalence of severe vitamin D deficiency was observed in 78.6% of chronic stable angina patients compared to 7.1% of controls.
• Vitamin D levels were identified as a significant predictor of chronic stable angina.
• Each unit increase in vitamin D level (ng/ml) was associated with a 0.30 times decrease in the odds of having chronic stable angina.

Conclusions:

• A significant association exists between vitamin D deficiency and the incidence of chronic stable angina.
• Vitamin D status is a crucial factor to consider in the context of cardiovascular health.
• Addressing vitamin D deficiency could be a potential strategy for managing chronic stable angina risk.