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Related Concept Videos

Introduction to Urinary System01:13

Introduction to Urinary System

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The urinary system consists of two kidneys, two ureters, the urinary bladder, and the urethra.
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Urinary Bladder01:23

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The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
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Disorders of the Urinary System01:20

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The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
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Electrical Current01:10

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Electrical current is defined as the rate at which charge flows. When there is a large current present, such as that used to run a refrigerator, a large amount of charge moves through the wire in a small amount of time. If the current is small, such as that used to operate a handheld calculator, a small amount of charge moves through the circuit over a long period of time. The SI unit for current is the ampere (A), named for the French physicist André-Marie Ampère (1775–1836).
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Natural and Artificial Concepts01:24

Natural and Artificial Concepts

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In psychology, concepts can be divided into two categories: natural and artificial. Natural concepts are formed through direct or indirect experiences. For example, consider the concept of snow. If you live in a place with regular snowfall, such as Essex Junction, Vermont, you know snow through direct experiences. You’ve seen it fall, touched it, shoveled it, and played in it. You recognize its texture, appearance, and even its smell. In contrast, if you live on an island like Saint...
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Potential Energy00:52

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The energy stored by a structure and location of matter in space is called potential energy. For instance, raising a kettlebell changes its spatial location and increases its potential energy. Similarly, a stretched rubber band contains potential energy which, under certain conditions, can be converted into other forms of energy, such as kinetic energy.
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Construction of a High Resolution Microscope with Conventional and Holographic Optical Trapping Capabilities
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Constructing artificial urinary conduits: current capabilities and future potential.

Jan Adamowicz1, Shane V Van Breda2, Tomasz Kloskowski1

  • 1a Chair of Urology, Department of Regenerative Medicine, Collegium Medicum , Nicolaus Copernicus University , Bydgoszcz , Poland.

Expert Review of Medical Devices
|December 28, 2018
PubMed
Summary
This summary is machine-generated.

Artificial urinary conduits offer a promising alternative to traditional intestinal segments for urinary diversion after cystectomy. Further research in large animal models is crucial for clinical translation.

Keywords:
Urinary conduitbiomaterialsreconstructive urologytissue engineeringtissue regeneration

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Area of Science:

  • Urology
  • Tissue Engineering
  • Regenerative Medicine

Background:

  • Intestinal segments, primarily ileal conduits (IC), are standard for urinary diversion post-cystectomy.
  • IC requires entero-enterostomy, a procedure linked to significant complications and prolonged recovery.
  • An artificial urinary conduit presents a potential alternative to improve outcomes.

Purpose of the Study:

  • To review current research on artificial urinary conduits.
  • To identify key challenges hindering the development and clinical application of these conduits.

Main Methods:

  • Literature review of existing research data on artificial urinary conduits.
  • Analysis of challenges and limitations in current experimental strategies.

Main Results:

  • Artificial urinary conduit fabrication is feasible with current tissue engineering technology.
  • Significant challenges remain in developing and validating these artificial conduits.

Conclusions:

  • Artificial urinary conduits hold promise for improved urinary diversion after cystectomy.
  • Extensive studies using large animal models with long-term follow-up are essential.
  • Data from such studies are critical for advancing translational research in this field.