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Updated: Jan 31, 2026

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
Published on: January 26, 2024
Polysaccharides-protein interaction of psyllium and whey protein with their texture and bile acid binding activity
Yuge Niu1, Qi Xia2, Wonhee Jung2
1Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing 10048, China; Institute of Food and Nutraceutical Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China.
Abstract:
Dietary fiber is a group of important food polysaccharides, which may improve gastrointestinal function and alter the bioavailability and nutritional value of other food components. The interaction mechanism of psyllium fiber (PSY) and whey protein (WP) and the influence on the characteristics of polysaccharides and protein were investigated. The results of circular dichroism spectra and differential scanning calorimetry analysis showed that PSY could protect WP by increasing its melting temperature. The textural profiles implied that WP could improve the edibility of the psyllium fiber. The IR spectrum and colorimetric assay indicated the product of Maillard reaction between psyllium and whey protein with the heating condition. The SEM showed that the structure of the mixture became stronger with higher temperature. Furthermore, the mixture with the ratio of WP/PSY as 1:2 had three times of the bile acid binding ability of PSY, which could be developed as a nutraceutical additive with prevention of hyperlipidemia.
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