Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peptidoglycan Synthesis01:28

Peptidoglycan Synthesis

2.4K
Structure of PeptidoglycanPeptidoglycan is a vital structural component of the bacterial cell wall, providing mechanical strength and shape to the cell. It consists of repeating units of two sugars—N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM)—linked by β-1,4 glycosidic bonds. These sugar chains are cross-linked by short peptide chains, forming a mesh-like polymer that surrounds the bacterial plasma membrane.Cytoplasmic Phase – Precursor SynthesisPeptidoglycan...
2.4K
Osmoregulation in Insects01:47

Osmoregulation in Insects

17.6K
Malpighian tubules are specialized structures found in the digestive systems of many arthropods, including most insects, that handle excretion and osmoregulation. The tubules are typically arranged in pairs and have a convoluted structure that increases their surface area.
17.6K
What is the Immune System?01:38

What is the Immune System?

127.9K
Overview
127.9K
Humoral Immune Responses01:36

Humoral Immune Responses

83.9K
Overview
83.9K
Conjugated Proteins02:50

Conjugated Proteins

28.7K
Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with non-protein moieties.
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
28.7K
Active versus Passive Immunity01:31

Active versus Passive Immunity

10.8K
Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
Active Immunity
Active immunity refers to the resistance one develops...
10.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Both Electrical Isolation and Lesion Homogeneity Should be Focused: Evidence From Repeat Atrial Fibrillation Ablation.

Journal of cardiovascular electrophysiology·2026
Same author

Selection and evaluation of dual reference genes in silkworm <i>(Bombyx mori</i>) based on transcriptome data.

Science progress·2026
Same author

Silkworm SOCS2 Differentially Promotes Multiple Steps of BmNPV Proliferation and Modulates the mRNA Expression of SOCS-STAT Network Components.

Insects·2026
Same author

Gel-Based 3D Food Printing for Dysphagia Management: Advances in Personalized Nutrition, Texture Control, and Clinical Translation.

Gels (Basel, Switzerland)·2026
Same author

Insect SVWC Proteins: A Diverse Cytokine-like Family Orchestrating Multilayered Antiviral and Antibacterial Immunity.

Insects·2026
Same author

Unraveling the causal cascade from atmospheric disturbances to ecosystem service degradation in open-pit mining areas.

Environmental research·2026

Related Experiment Video

Updated: Jan 31, 2026

A Method For Production of Recombinant mCD1d Protein in Insect Cells.
09:41

A Method For Production of Recombinant mCD1d Protein in Insect Cells.

Published on: December 10, 2007

11.2K

Peptidoglycan recognition proteins in insect immunity.

Qiang Wang1, Meijia Ren2, Xiaoyong Liu2

  • 1School of Food and Biological Engineering, Jiangsu University, Zhenjiang, Jiangsu, PR China; Institute of Life Sciences, Jiangsu University, Zhenjiang, Jiangsu, PR China.

Molecular Immunology
|December 28, 2018
PubMed
Summary

Insects rely on their innate immune system, particularly peptidoglycan recognition proteins (PGRPs), to fight microbial infections by recognizing pathogen-associated molecular patterns (PAMPs). This review details PGRPs

Keywords:
Antimicrobial peptidesInnate immuneThe peptidoglycan recognition proteinsToll, IMD and PPO pathway

More Related Videos

Immunofluorescent Labeling of Plant Virus and Insect Vector Proteins in Hemipteran Guts
07:16

Immunofluorescent Labeling of Plant Virus and Insect Vector Proteins in Hemipteran Guts

Published on: May 14, 2021

2.1K
Semi-Quantitative Analysis of Peptidoglycan by Liquid Chromatography Mass Spectrometry and Bioinformatics
09:09

Semi-Quantitative Analysis of Peptidoglycan by Liquid Chromatography Mass Spectrometry and Bioinformatics

Published on: October 13, 2020

5.1K

Related Experiment Videos

Last Updated: Jan 31, 2026

A Method For Production of Recombinant mCD1d Protein in Insect Cells.
09:41

A Method For Production of Recombinant mCD1d Protein in Insect Cells.

Published on: December 10, 2007

11.2K
Immunofluorescent Labeling of Plant Virus and Insect Vector Proteins in Hemipteran Guts
07:16

Immunofluorescent Labeling of Plant Virus and Insect Vector Proteins in Hemipteran Guts

Published on: May 14, 2021

2.1K
Semi-Quantitative Analysis of Peptidoglycan by Liquid Chromatography Mass Spectrometry and Bioinformatics
09:09

Semi-Quantitative Analysis of Peptidoglycan by Liquid Chromatography Mass Spectrometry and Bioinformatics

Published on: October 13, 2020

5.1K

Area of Science:

  • Insect immunology
  • Molecular biology
  • Biochemistry

Background:

  • Insects possess only an innate immune system to combat microbial infections.
  • Innate immunity relies on pattern recognition receptors (PRRs) interacting with pathogen-associated molecular patterns (PAMPs).
  • Peptidoglycan recognition proteins (PGRPs) are crucial insect PRRs that recognize peptidoglycan (PGN).

Purpose of the Study:

  • To summarize the structure, classification, and function of insect PGRPs.
  • To discuss the vital role of PGRPs in insect innate immunity.

Main Methods:

  • Literature review and synthesis of existing research on PGRPs.
  • Analysis of PGRP structure, classification, and functional data.

Main Results:

  • PGRPs are a key family of PRRs in insects.
  • PGRPs recognize peptidoglycan (PGN), a major component of bacterial cell walls.
  • PGRPs are essential for mounting an effective innate immune response against microbial pathogens.

Conclusions:

  • PGRPs are indispensable for insect innate immunity.
  • Understanding PGRPs provides insights into insect defense mechanisms against pathogens.
  • Further research into PGRPs can inform strategies for insect disease control.