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Antidepressant medication might increase the risk of self-harm injuries: findings in 17 OECD countries
Göran N Högberg1, Sven G Bremberg2,3
1Formerly Department of Women's and Children's Health, Child and Adolescent Psychiatric Unit, Karolinska Institute, Stockholm, Sweden.
Abstract:
Clinical trials suggest that antidepressants increase the risk of self-harm injuries (SHI). The aim was to investigate associations between antidepressants' use and the rate of change of SHI in 17 countries over the period 2000-16, with initial levels of SHI taken into account. The rate of change of SHI seems mainly (81%) determined by initial rates. The rate of SHI decreased in most countries. The decrease was slower in countries with a high level of antidepressants' use and in countries with an increase of depressive disorders. The study indicates that the use of antidepressants might increase the risk of SHI.
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