Related Experiment Video
Updated: Jan 31, 2026

10:17
Guidelines and Experience Using Imaging Biomarker Explorer IBEX for Radiomics
Published on: January 8, 2018
13.7K
Radiogenomics and Radiomics in Liver Cancers
Aman Saini1, Ilana Breen2, Yash Pershad3
1Division of Vascular and Interventional Radiology, Minimally Invasive Therapeutics Laboratory, Mayo Clinic, Phoenix, AZ 85054, USA. Saini.Aman@mayo.edu.
Diagnostics (Basel, Switzerland)
|December 29, 2018
Summary
Radiogenomics and radiomics analyze medical images to predict tumor molecular profiles and guide treatment. These fields transform imaging into a quantitative tool for understanding liver cancer.
Area of Science:
- Computational imaging analysis
- Biomedical imaging
- Translational oncology
Background:
- Radiogenomics links imaging features with molecular data for non-invasive tumor profiling.
- Radiomics extracts quantitative data from images for prognosis and clinical decisions.
- These fields are advancing medical imaging from descriptive to predictive.
Purpose of the Study:
- To review recent advancements in radiogenomics and radiomics for liver cancers.
- To highlight the potential of these computational disciplines in oncology.
Main Methods:
- Review of current literature on radiogenomics and radiomics in liver cancer.
- Analysis of studies correlating imaging phenotypes with molecular data.
- Integration of quantitative imaging data with clinical information.
Main Results:
- Radiogenomics enables non-invasive prediction of tumor molecular characteristics.
- Radiomics provides prognostic information and aids clinical decision-making.
- Combined, these fields offer insights into pathophysiological mechanisms of liver cancer.
Conclusions:
- Radiogenomics and radiomics are transforming liver cancer diagnosis and management.
- These disciplines facilitate a deeper understanding of liver cancer through advanced imaging analysis.
- Future applications may further enhance personalized treatment strategies for liver malignancies.
Keywords:
hepatocellular carcinomaintrahepatic cholangiocarcinomaliver metastasisradiogenomicsradiomicsMore Related Videos
Related Concept Videos
Liver Histology
4.4K
The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
Hepatocytes perform a variety of essential functions. They secrete...
Hepatocytes perform a variety of essential functions. They secrete...
4.4K
Liver Physiology
3.7K
The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
3.7K
Liver Regeneration
4.3K
The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
4.3K
Gross Anatomy of the Liver
2.1K
The liver, the largest gland within the human body, is a firm and reddish-brown organ. This wedge-shaped structure weighs approximately 1.5 kg and occupies a significant portion of the right hypochondriac and epigastric regions. It extends more to the right of the body's midline than to the left.
Located under the diaphragm, the liver is almost entirely ensconced within the rib cage, providing it with substantial protection. Except for the superior most bare area, the liver's surface is...
Located under the diaphragm, the liver is almost entirely ensconced within the rib cage, providing it with substantial protection. Except for the superior most bare area, the liver's surface is...
2.1K
Diseases of the Liver and Gallbladder
2.0K
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
2.0K
Cancer
54.3K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
54.3K

