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A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
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Pregnancies Complicated by Familial Hypertriglyceridemia: A Case Report
Suzanne Cao1, NhuChi Dao1, Kristina Roloff1
1Department of Women's Health, Arrowhead Regional Medical Center, Colton, California.
AJP Reports
|December 29, 2018
Summary
Familial hypertriglyceridemia during pregnancy can be dangerous. Gemfibrozil treatment may prevent serious complications like pancreatitis and diabetic ketoacidosis, showing its safety and effectiveness in pregnant patients.
Area of Science:
- Obstetrics and Gynecology
- Cardiology
- Endocrinology
Background:
- Familial hypertriglyceridemia is a rare but serious condition during pregnancy.
- It can lead to life-threatening complications such as pancreatitis and diabetic ketoacidosis.
Observation:
- Two case studies highlight pregnancies complicated by familial hypertriglyceridemia.
- Patient 1 experienced recurrent pancreatitis due to noncompliance with gemfibrozil in her first pregnancy.
- Patient 2 managed diabetes and familial hypertriglyceridemia, with gemfibrozil compliance preventing hypertriglyceridemia-related issues.
Findings:
- Gemfibrozil treatment appeared to prevent severe hypertriglyceridemia complications in both pregnancies.
- Medication compliance was crucial for positive maternal and fetal outcomes.
- No adverse maternal or fetal effects were noted with gemfibrozil use.
Implications:
- Gemfibrozil may be a safe and effective treatment option for severe hypertriglyceridemia in pregnant individuals.
- Emphasizes the critical role of patient adherence to medication regimens.
- Highlights the need for careful management of hypertriglyceridemia during pregnancy.
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