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Salmonella Typhimurium para-aortic root abscess managed non-surgically
Tarek Haykal1,2, Abdul Rahman Al Bizri3, Thair Dawood1,2
1Hurley Medical Center, Department of Internal Medicine, Flint, MI, USA.
Introduction:
Para-aortic root abscess is a destructive vascular condition that can result in significant morbidity and mortality. We describe a rare case of para-aortic root abscess due to Salmonella Typhimurium that was successfully managed medically.
Presentation Of Case:
A 72-year-old diabetic man with a prosthetic aortic graft presented with fever and expressive aphasia with left sided weakness. Magnetic resonance imaging (MRI) of the brain showed multiple embolic cerebral vascular accidents. Computed tomography angiography (CTA) of the chest showed a 5.7 × 2.7 cm (cm) para-aortic root abscess. Blood cultures grew Salmonella Typhimurium. The patient was started on ceftriaxone initially, and then ciprofloxacin was added on day 5. Given an unacceptably high risk of mortality expected with surgery, the patient was managed medically.After five months of both ceftriaxone and ciprofloxacin, ceftriaxone was stopped. Twelve months later, the patient is doing well on ciprofloxacin alone with a plan for lifelong suppression.
Discussion:
Cases of para-aortic root abscess due to Salmonella Typhimurium have not been reported in the literature. There are no guidelines to dictate the antibiotic choice or management of para-aortic root abscess due to Salmonella Typhimurium.
Conclusion:
This report adds to the body of literature regarding the treatment of this infection including successful non-surgical management.
Insights
A rare para-aortic root abscess caused by Salmonella Typhimurium was successfully treated with antibiotics alone. This case highlights effective medical management for this destructive vascular condition, avoiding high-risk surgery.
Area of Science:
- Vascular Surgery
- Infectious Diseases
- Medical Microbiology
Background:
- Para-aortic root abscess is a serious vascular condition associated with high morbidity and mortality.
- Infections involving Salmonella Typhimurium in this region are exceptionally rare and lack established treatment guidelines.
Purpose of the Study:
- To report a unique case of para-aortic root abscess caused by Salmonella Typhimurium.
- To describe the successful medical management of this rare condition.
Main Methods:
- A 72-year-old male with a prosthetic aortic graft presented with symptoms of embolic stroke and fever.
- Diagnostic imaging revealed a large para-aortic root abscess.
- Blood cultures identified Salmonella Typhimurium, and the patient was treated with a prolonged course of intravenous and oral antibiotics.
Main Results:
- The patient showed a positive response to antibiotic therapy, specifically ceftriaxone and ciprofloxacin.
- Surgical intervention was deemed too high-risk, and medical management was pursued.
- After 17 months of treatment, the patient remains clinically well on suppressive antibiotic therapy.
Conclusions:
- Successful medical management of para-aortic root abscess due to Salmonella Typhimurium is possible.
- This case expands treatment options for rare vascular infections, demonstrating the efficacy of non-surgical approaches.
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