Related Experiment Video
Updated: Jan 31, 2026

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
Published on: February 13, 2020
The Association of Motor Skills and Adaptive Functioning in XXY/Klinefelter and XXYY Syndromes
Sydney Martin1,2, Lisa Cordeiro3, Pamela Richardson2
1a Occupational Therapy Department , Children's Hospital Colorado , Aurora , Colorado , USA.
Abstract:
Aims: Klinefelter (XXY) and XXYY syndromes are genetic disorders in males characterized by additional sex chromosomes compared to the typical male karyotype of 46, XY. Both conditions have been previously associated with motor delays and motor skills deficits. We aimed to describe and compare motor skills in males with XXY and XXYY syndromes, and to analyze associations with age, cognitive abilities, and adaptive functioning. Methods: Sixty-four males with XXY and 46 males with XXYY, ages 4-20 were evaluated using the Beery Test of Visual Motor Integration and the Bruininks-Oseretsky Test of Motor Proficiency - 2nd Edition assessments, Vineland-2 adaptive scales, and cognitive testing. Results: Motor coordination impairments were found in 39% of the males with XXY and 73% of the males with XXYY. Both groups showed strengths in visual perceptual skills. Males with XXYY had lower mean scores compared to males with XXY across all assessments. Fine motor dexterity and coordination deficits were common. There was a positive correlation between VMI scores and adaptive functioning. Conclusion: Occupational and physical therapists should be aware of the motor phenotype in XXY and XXYY both to aid in diagnosis of unidentified cases and to guide intervention.
More Related Videos
07:52Investigating Motor Skill Learning Processes with a Robotic Manipulandum
Published on: February 12, 2017
08:51Author Spotlight: Unveiling Neural Mechanisms Through Automated Evaluation of Motor Learning and Myelin Plasticity Studies Using the Erasmus Ladder
Published on: December 15, 2023
Related Concept Videos
Somatosensory, Motor, and Association Cortex
Association Areas of the Cortex
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Associative Learning
Classical conditioning, also known...
Factors Influencing Attraction V: Social Skills
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Nephrotic Syndrome I : Introduction