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Updated: Jan 31, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Surface-based registration between CT and US for image-guided percutaneous renal access - A feasibility study
João Gomes-Fonseca1,2, Sandro Queirós1,2,3, Pedro Morais1,2,3
1Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
This study demonstrates that combining computed tomography (CT) and ultrasound (US) data using surface-based registration improves percutaneous renal access (PRA). An optimal 2D US acquisition protocol was identified for enhanced image-guided PRA procedures.
Area of Science:
- Medical Imaging
- Surgical Navigation
- Biomedical Engineering
Background:
- Percutaneous renal access (PRA) is vital for minimally invasive kidney interventions.
- Improving the practicality and safety of PRA can be achieved by fusing computed tomography (CT) and ultrasound (US) data.
- Surface-based registration techniques offer potential for accurate image fusion.
Purpose of the Study:
- To assess the potential of a surface-based registration technique for fusing 2D US and CT data.
- To establish an optimal US acquisition protocol for image-guided PRA.
- To improve the practicality and safety of percutaneous renal access.
Main Methods:
- Ten porcine kidney phantoms were imaged using CT and 3D US.
- Surface-based registration was performed using iterative closest point algorithms (ICP1, ICP2).
- Four acquisition variants were studied, evaluating different views, coverage ranges, sweep movements, and slice spacing.
Main Results:
- The bi-plane (BP) view combined with the ICP2 method, wide kidney coverage, and specific sweep movements yielded the best performance (TRE = 2.26 mm).
- This performance was statistically similar to full 3D US surface registration (TRE = 2.28 mm).
- An optimal 2D US acquisition protocol was identified.
Conclusions:
- Surface-based registration using multiple slices and optimized sweep movements/views is a valid strategy for intraoperative CT-US image fusion.
- This approach has the potential to enhance image-guided percutaneous renal access.
- The technique may be applicable to other imaging modalities and interventions.
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