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[Progress relationship between periostin and periodontitis].

Qian Liu1, Ping Huang1, Shu-Juan Guo1

  • 1State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Periodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.

Hua Xi Kou Qiang Yi Xue Za Zhi = Huaxi Kouqiang Yixue Zazhi = West China Journal of Stomatology
|December 29, 2018
PubMed
Summary
This summary is machine-generated.

Periostin, a protein crucial for periodontal ligament integrity, aids in periodontitis recovery. This review explores its role in periodontal tissue and disease processes.

Keywords:
periodontal tissueperiodontitisperiostin

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Area of Science:

  • Biomedical Science
  • Oral Biology
  • Regenerative Medicine

Background:

  • Periostin is a matricellular protein highly expressed in periodontal ligament and periosteum.
  • It plays a significant role in maintaining the integrity of periodontal tissues.
  • Periostin is implicated in the pathogenesis and progression of periodontitis.

Purpose of the Study:

  • To review the existing literature on the role of periostin in periodontal tissue.
  • To elucidate the function of periostin in periodontitis.
  • To highlight periostin's potential in periodontitis treatment and recovery.

Main Methods:

  • Literature review of scientific articles.
  • Analysis of studies on periostin expression and function.
  • Synthesis of data regarding periostin's involvement in periodontal health and disease.

Main Results:

  • Periostin is essential for the structural integrity of the periodontal ligament.
  • Periostin demonstrates a positive influence on the healing and recovery processes in periodontitis.
  • Its expression levels correlate with the severity and progression of periodontal disease.

Conclusions:

  • Periostin is a key regulator of periodontal tissue homeostasis.
  • Targeting periostin may offer therapeutic strategies for periodontitis.
  • Further research into periostin's mechanisms can advance periodontal regenerative therapies.