Clinical, demographic, risk factor and angiographic profile of coronary slow flow phenomenon: A single centre

Sanjeev Sanghvi1, Rohit Mathur1, Anil Baroopal1

  • 1Department of Cardiology, DR. S.N. Medical College, Jodhpur, India.

Indian Heart Journal
|January 1, 2019
PubMed

Insights

The coronary slow flow phenomenon (CSFP) is linked to hypertension, dyslipidemia, and tobacco use. These risk factors are independently associated with CSFP, indicating it

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Coronary Artery Disease

Background:

  • Coronary slow flow phenomenon (CSFP) is an angiographic finding of delayed distal vessel opacification without significant stenosis.
  • The exact causes of CSFP remain unclear despite being known for decades.

Purpose of the Study:

  • To determine the clinical, demographic, risk factor, and angiographic profile of patients with CSFP.
  • To identify factors associated with the development of CSFP.

Main Methods:

  • Consecutive patients undergoing coronary angiography between September 2016 and March 2017 were analyzed.
  • Patients with CSFP were compared to a control group with normal coronary flow (NCF).
  • CSFP diagnosis was based on the corrected thrombolysis in myocardial infarction frame count.

Main Results:

  • CSFP was more prevalent in males.
  • Hypertension, dyslipidemia, and tobacco use were significantly more common in CSFP patients.
  • Multivariable analysis revealed hypertension, dyslipidemia, smoking, and tobacco chewing as independent risk factors for CSFP.
  • Acute coronary syndrome (ACS) was the most frequent presentation in CSFP patients.

Conclusions:

  • CSFP is common in patients presenting with ACS.
  • Hypertension, dyslipidemia, smoking, and tobacco chewing are independent risk factors for CSFP.
  • CSFP should be regarded as a pathological entity, not a benign condition.
Abstract

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