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Published on: June 14, 2024
Door-to-balloon time and the determining factors in a tertiary cardiac center in Nepal
Sachin Dhungel1, Rabi Malla2, Chandramani Adhikari2
1College of Medical Sciences, Nepal; Interventional Cardiology Fellow Training, SGNHC, Nepal.
Insights
The median door-to-balloon time for primary angioplasty was 79 minutes, falling below the 90-minute benchmark. Key factors influencing this time were hospital visit timing and patient transfer status.
Area of Science:
- Cardiology
- Interventional Cardiology
- Public Health
Background:
- Door-to-balloon (DTB) time is a critical metric in primary angioplasty, with a 90-minute benchmark.
- Shorter DTB times are associated with improved clinical outcomes.
- Longer DTB times can lead to poorer patient prognosis.
Purpose of the Study:
- To evaluate the median DTB time in patients undergoing primary angioplasty.
- To identify factors influencing DTB time.
- To assess adherence to the 90-minute benchmark.
Main Methods:
- A 3-month cross-sectional observational study was conducted at Shahid Gangalal National Heart Center.
- Included all patients undergoing primary angioplasty.
- DTB time was calculated, and various potential determinants were analyzed.
Main Results:
- The median DTB time was 79 minutes (IQR 59-115 min), with 58.2% of patients achieving <90 min.
- Significant variations in DTB time were observed based on direct vs. transfer status (p=0.029) and office vs. off-hours visits (p=0.012).
- No significant differences in DTB time were found related to infarct-related vessels, number of vessels involved, added procedures, age, gender, hypertension, diabetes, heart failure, or LVEF.
Conclusions:
- The median DTB time for primary angioplasty in this study was below the 90-minute benchmark.
- Hospital visit timing and patient origin (direct admission vs. transfer) were significant determinants of DTB time.
- Opportunities exist to further optimize factors influencing DTB time to achieve even shorter durations.
Background:
Door-to-balloon (DTB) time of 90 min during primary angioplasty is considered as the benchmark duration. Shorter DTB time is preferable, and longer duration can have poor clinical outcomes.
Methods:
A cross-sectional observational study of three months in Shahid Gangalal National Heart Center was conducted in which all patients undergoing primary angioplasty were included. The DTB time was calculated, and the different determining factors were studied.
Results:
Seventy-nine patients undergoing primary percutaneous intervention were studied. The median DTB time was 79 minutes (Interquartile range [IQR] 59-115 min). Forty-six (58.2%) patients had a DTB time of less than 90 min. DTB time varied significantly with direct visit vs transfer (p = 0.029) and office time visit (9 am-5 pm) vs off time (5 pm-9 am) (p = 0.012). DTB time did not differ between any infarct-related vessels (p = 0.471), number of vessels involved (p = 0.638), and the added procedures (defibrillation, thrombosuction, and temporary pacemaker insertion) (p = 0.682) during angioplasty. No significant differences were recorded according to age (p = 0.330), gender (p = 0.254), hypertension (p = 0.073), diabetes (p = 0.487), heart failure (p = 0.316), and baseline left ventricular ejection fraction (LVEF) (p = 0.819).
Conclusion:
The median DTB time in primary angioplasty was less than 90 minutes. The significant determining factors were timing of hospital visit (office vs off time) and type of visit (direct vs transfer). There can be improvement in factors determining DTB time to lower it further.
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