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Chronic mandibular osteomyelitis caused by Granulicatella adiacens in an immunocompetent child
Kazuyoshi Mizuki1, Hiromi Morita1, Takayuki Hoshina1
1Department of Pediatrics, School of Medicine, University of Occupational and Environmental Health, Japan.
Abstract:
We report a pediatric case aged 10 years with Granulicatella adiacens-associated chronic mandibular osteomyelitis. The causative pathogen was uncertain because polymicrobial species were detected from the bacterial culture in bone marrow fluid. In contrast, G. adiacens was predominantly identified in the clone library analysis of the bacterial 16S rRNA gene sequence. Vancomycin to which G. adiacens was reported to be susceptible was not administrated sufficiently to this patient because of its adverse event, whereas linezolid and ciprofloxacin was alternatively effective for the treatment of chronic mandibular osteomyelitis.
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