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Updated: Jan 31, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Endovascular therapy for subclavian artery restenosis due to stent strut protrusion with high-resolution angioscopy
Kuniyasu Ikeoka1, Keita Okayama2, Tetsuya Watanabe1
1Department of Cardiovascular Medicine, Yao Municipal Hospital, Yao, Osaka, Japan.
Insights
Severe chest pain in a patient with prior bypass surgery was linked to left subclavian artery stenosis. Advanced imaging confirmed stent issues, enabling successful endovascular treatment and improved outcomes.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Medical Imaging
Background:
- Patient presented with effort angina and a history of coronary artery bypass grafting and stenting for left subclavian and vertebral artery stenoses.
- Myocardial perfusion imaging indicated ischemia, prompting investigation into the previously treated arterial stenoses.
Observation:
- Endovascular therapy was employed to treat the left subclavian artery stenosis.
- High-resolution angioscopy and optical frequency domain imaging (OFDI) revealed a vertebral Palmaz stent protruding from the ostium.
- The protruding stent strut was observed to jail the left subclavian artery.
Findings:
- Three-dimensional OFDI confirmed successful guidewire passage through the Palmaz stent strut.
- Balloon angioplasty was performed to dilate the deformed stent strut.
- The intervention aimed to resolve cardiac ischemia caused by the subclavian stenosis.
Implications:
- New imaging technologies, including high-resolution angioscopy and 3D-OFDI, enhance visualization during endovascular procedures.
- These technologies improve the safety and efficacy of craniocervical interventions by allowing detailed observation of stent deployment.
- Successful guidewire crossing and dilation of a deformed stent strut demonstrate the utility of advanced imaging in complex peripheral artery disease cases.
Abstract:
A 47-year-old female patient was admitted with a complaint of severe chest pain on effort. She had a history of effort angina treated using coronary artery bypass with left internal thoracic arterial bypass to the left ascending coronary artery. She also had left subclavian and vertebral arterial stenoses, which were treated with balloon-expandable stents. Exercise stress myocardial perfusion imaging revealed anterior to apex left ventricular myocardial ischemia. Cardiac ischemia due to left subclavian stenosis was diagnosed. We treated the left subclavian arterial stenosis with endovascular therapy. We observed that the vertebral Palmaz stent protruded from the ostium and the jailed subclavian artery on high-resolution angioscopy (Zemporshe with a 0.48-megapixel equivalent resolution; Taisho Biomed Instruments, Osaka, Japan) and optical frequency domain imaging (OFDI). A guide wire was successfully crossed through the Palmaz stent strut, which was confirmed using three-dimensional OFDI. The stent strut was dilated using balloon angioplasty. New imaging technologies are promising tools for improving the efficacy and safety of craniocervical intervention. <Learning objective: New imaging technologies including high-resolution angioscopy and 3D-optical frequency domain imaging have become available for endovascular therapy of peripheral artery disease. They could be used to observe stent strut deformation with high imaging quality and demonstrated successful guidewire passage through the stent strut. High-resolution angioscopic system yields images with higher quality and larger angular field than any other previous angioscopy systems.>.
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