Prevalence of Erythrocyte Changes in Patients with Heart Failure

Heart failure (HF) is one of the most common causes of hospitalization in patients over the age of 65. Purpose The objective of our study was to assess the prevalence of anemia and characterize the morphology of red blood cells in patients admitted for HF decompensation. Material and Methods We have included patients with decompensated HF with left ventricular ejection fraction (LVEF). ≤45% successively hospitalized at Filantropia Clinical Hospital Craiova. Results A total of 397 patients, including 204 males (51.39%) were included. The prevalence of anemia in our group was 38.54% (153 patients). The mean age of patients with heart failure and anemia was significantly higher compared to those with normal hemoglobin (75.05±7.16 years vs. 72.27±7.91 years, p=0.00047). The majority of anemias (68.62%) were normocytic normochromic, defined as mean corpuscular hemoglobin (MCV) value between 80 to 98fl and mean corpuscular hemoglobin concentration (MCH)>27pg. 20 patients (13.07%) had microcytic hypochromic anemia (MCV<80fL and MCH<27pg), in 16 patients (10.45%) was present normocytic hypochromic anemia (MCV 80-98fl and MCH<27pg) and 12 patients (7.48%) had macrocytic anemia (MCV>98fL and MCH>27pg), respectively. Conclusions Our study suggests that the prevalence of anemia in hospitalized patients for HF decompensation is high and normocytic normochromic anemia was the most common morphological type of anemia.