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Related Concept Videos

Pancreas01:19

Pancreas

2.4K
The pancreas, an essential organ in the human body, is a pinkish-gray elongated structure located posterior to the stomach. It extends laterally from the duodenum towards the spleen and is firmly bound to the posterior wall of the abdominal cavity. The organ's surface has a lumpy, lobular texture that gives it a unique appearance.
The broad head of the pancreas lies within the loop formed by the duodenum, while its slender body reaches towards the spleen. The tail of the pancreas is short...
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Metallic Solids02:37

Metallic Solids

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Metallic solids such as crystals of copper, aluminum, and iron are formed by metal atoms. The structure of metallic crystals is often described as a uniform distribution of atomic nuclei within a “sea” of delocalized electrons. The atoms within such a metallic solid are held together by a unique force known as metallic bonding that gives rise to many useful and varied bulk properties.
All metallic solids exhibit high thermal and electrical conductivity, metallic luster, and malleability....
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Structures of Solids02:22

Structures of Solids

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Solids in which the atoms, ions, or molecules are arranged in a definite repeating pattern are known as crystalline solids. Metals and ionic compounds typically form ordered, crystalline solids. A crystalline solid has a precise melting temperature because each atom or molecule of the same type is held in place with the same forces or energy. Amorphous solids or non-crystalline solids (or, sometimes, glasses) which lack an ordered internal structure and are randomly arranged. Substances that...
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Network Covalent Solids02:18

Network Covalent Solids

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Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
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Cells and Secretions of the Pancreas01:16

Cells and Secretions of the Pancreas

5.3K
The pancreas, a vital organ within the abdominal cavity, plays dual roles in the digestive and endocrine systems, collaborating with exocrine and endocrine cells to maintain optimal digestion and blood sugar levels.
Exocrine function is carried out by acinar cells, organized into clusters known as acini. These cells contribute to digestion by releasing substantial quantities of enzyme-rich, alkaline digestive juices.
Concurrently, the dispersed clusters of endocrine cells throughout the...
5.3K
Molecular and Ionic Solids02:54

Molecular and Ionic Solids

20.1K
Crystalline solids are divided into four types: molecular, ionic, metallic, and covalent network based on the type of constituent units and their interparticle interactions.
Molecular Solids
Molecular crystalline solids, such as ice, sucrose (table sugar), and iodine, are solids that are composed of neutral molecules as their constituent units. These molecules are held together by weak intermolecular forces such as London dispersion forces, dipole-dipole interactions, or hydrogen bonds, which...
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Related Experiment Video

Updated: Jan 31, 2026

Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Pancreas Allografts before Transplantation
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Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Pancreas Allografts before Transplantation

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Solid pancreas transplant: Pushing forward.

Emmanouil Giorgakis1, Amit K Mathur1, Harini A Chakkera2

  • 1Division of Transplant, Department of Surgery, Mayo Clinic, Phoenix, AZ 85054, United States.

World Journal of Transplantation
|January 1, 2019
PubMed
Summary
This summary is machine-generated.

Pancreas transplantation is a viable option for type 1 diabetes patients. Improving organ procurement and considering expanded donor criteria could increase pancreas allograft utilization and benefit more diabetic patients.

Keywords:
Donations after cardiac death pancreas transplantObese pancreas donorsPancreas transplantPancreas transplant for type 2 diabetesWhole pancreas transplant

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Mouse Model for Pancreas Transplantation Using a Modified Cuff Technique
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Last Updated: Jan 31, 2026

Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Pancreas Allografts before Transplantation
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Mouse Model for Pancreas Transplantation Using a Modified Cuff Technique
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Mouse Model for Pancreas Transplantation Using a Modified Cuff Technique

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Surgical Tips and Tricks for Performing Porcine Pancreas Transplantation

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Area of Science:

  • Transplantation immunology
  • Endocrinology
  • Nephrology

Background:

  • Pancreas transplantation has advanced, offering a treatment for type 1 diabetes patients with complications like end-stage kidney disease.
  • Despite advancements, significant underutilization of donor pancreata persists, with high allograft discard rates.

Purpose of the Study:

  • To review the historical development of pancreas transplantation.
  • To identify current barriers hindering wider pancreas transplant utilization.
  • To suggest future improvements for enhanced pancreas transplant care.

Main Methods:

  • Review of historical origins and current practices in pancreas transplantation.
  • Analysis of organ procurement challenges and allograft discard rates.
  • Examination of strategies to improve organ utilization, including from specific donor types.

Main Results:

  • Donor pancreata are underutilized, with approximately 30% discarded in the United States.
  • Pancreata from donors after cardiac death (DCD) are rarely procured.
  • Professionalized procurement and standardized techniques can improve efficiency and reduce discards.

Conclusions:

  • Pancreas transplant programs should explore procurement from DCD and obese donors.
  • Consideration of selected type 2 diabetic patients for pancreas transplantation is warranted.
  • Long-term studies are needed to confirm cardiovascular and quality-of-life benefits, supporting broader application.