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Updated: Jan 31, 2026

A Miniaturized Glycan Microarray Assay for Assessing Avidity and Specificity of Influenza A Virus Hemagglutinins
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Fluorescent Trimeric Hemagglutinins Reveal Multivalent Receptor Binding Properties

Nikoloz Nemanichvili1, Ilhan Tomris2, Hannah L Turner3

  • 1Pathology Division, Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, 3584, CL, Utrecht, the Netherlands.

Journal of Molecular Biology
|January 1, 2019
PubMed
Summary

Influenza hemagglutinin (HA) proteins fused with sfGFP visualize host cell interactions. Avian-specific HA requires multimerization for binding on arrays, unlike human-specific HA, suggesting distinct binding mechanisms.

Keywords:
Influenzaattachment proteinbidentatemultivalentprecomplexing

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