Household renovation before and during pregnancy in relation to preterm birth and low birthweight in China

Wei Liu1,2, Chen Huang3, Baizhan Li4

  • 1Department of Building Science, Tsinghua University, Beijing, China.

Indoor Air
|January 1, 2019
PubMed

Insights

Household renovation before pregnancy is linked to low birthweight (LBW) and term low birthweight (Term-LBW). Renovation during pregnancy is associated with preterm birth (PTB), highlighting environmental risks to child health.

Area of Science:

  • Environmental Health
  • Maternal and Child Health
  • Epidemiology

Background:

  • Household environments significantly influence child health outcomes.
  • Early life exposures, including renovation, may pose risks to fetal development.

Purpose of the Study:

  • To investigate the association between household renovation and adverse birth outcomes in Chinese preschool children.
  • To analyze the impact of renovation timing (pre-pregnancy vs. during pregnancy) on preterm birth (PTB), low birthweight (LBW), term low birthweight (Term-LBW), and small for gestational age (SGA).

Main Methods:

  • Cross-sectional study of 25,813 preschool children in eight Chinese cities (2010-2012).
  • Parental questionnaires collected data on household renovation, gestational age, and birthweight.
  • Multivariate and two-level logistic regression analyses were employed.

Main Results:

  • Household renovation in the year before pregnancy was significantly associated with LBW (OR: 1.23, 95% CI: 1.01-1.50) and Term-LBW (OR: 1.29, 95% CI: 1.01-1.67).
  • Household renovation during pregnancy was significantly associated with PTB (OR: 1.28, 95% CI: 1.01-1.69).
  • Associations were robust in sensitivity and subgroup analyses.

Conclusions:

  • Household renovation within one year pre-pregnancy may increase the risk of LBW and Term-LBW.
  • Household renovation during pregnancy may increase the risk of PTB.
  • Findings suggest household renovation is a potential environmental risk factor impacting birth outcomes.

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