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Published on: January 12, 2018
Household renovation before and during pregnancy in relation to preterm birth and low birthweight in China
Wei Liu1,2, Chen Huang3, Baizhan Li4
1Department of Building Science, Tsinghua University, Beijing, China.
Insights
Household renovation before pregnancy is linked to low birthweight (LBW) and term low birthweight (Term-LBW). Renovation during pregnancy is associated with preterm birth (PTB), highlighting environmental risks to child health.
Area of Science:
- Environmental Health
- Maternal and Child Health
- Epidemiology
Background:
- Household environments significantly influence child health outcomes.
- Early life exposures, including renovation, may pose risks to fetal development.
Purpose of the Study:
- To investigate the association between household renovation and adverse birth outcomes in Chinese preschool children.
- To analyze the impact of renovation timing (pre-pregnancy vs. during pregnancy) on preterm birth (PTB), low birthweight (LBW), term low birthweight (Term-LBW), and small for gestational age (SGA).
Main Methods:
- Cross-sectional study of 25,813 preschool children in eight Chinese cities (2010-2012).
- Parental questionnaires collected data on household renovation, gestational age, and birthweight.
- Multivariate and two-level logistic regression analyses were employed.
Main Results:
- Household renovation in the year before pregnancy was significantly associated with LBW (OR: 1.23, 95% CI: 1.01-1.50) and Term-LBW (OR: 1.29, 95% CI: 1.01-1.67).
- Household renovation during pregnancy was significantly associated with PTB (OR: 1.28, 95% CI: 1.01-1.69).
- Associations were robust in sensitivity and subgroup analyses.
Conclusions:
- Household renovation within one year pre-pregnancy may increase the risk of LBW and Term-LBW.
- Household renovation during pregnancy may increase the risk of PTB.
- Findings suggest household renovation is a potential environmental risk factor impacting birth outcomes.
Abstract:
From October 2010 to April 2012, we conducted a cross-sectional study of associations between household environments and childhood health among preschool children in eight Chinese cities. Here, we analyze associations of early household renovation with preterm birth (PTB), low birthweight (LBW), term low birthweight (Term-LBW), and small for gestational age (SGA). Parents responded to questions about household renovation and their children's gestational age and birthweight. In the multivariate logistic regression analyses, household renovation in the year before pregnancy was significantly associated with LBW (sample size: N = 25 813; adjusted odds ratio (OR) with 95% confidence intervals (CIs): 1.23, 1.01-1.50) and Term-LBW (N = 24 823; 1.29, 1.01-1.67). Household renovation during pregnancy was significantly associated with PTB (N = 25 202; 1.28, 1.01-1.69). These significant associations were also found in the two-level (city-child) logistic regression analyses and in the sensitivity analyses among 21 009 children with complete data in all studied variates. Stronger associations were found in certain subgroups. Our findings indicate that household renovation within one year before pregnancy might be a risk factor for LBW and Term-LBW, while household renovation during pregnancy could be a risk factor for PTB.
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