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Adult-Onset Atopic Dermatitis.
1Departments of Dermatology, Preventive Medicine and Medical Social Sciences, Feinberg School of Medicine at Northwestern University, Chicago, Ill; Northwestern Medicine Multidisciplinary Eczema Center, Chicago, Ill.
The Journal of Allergy and Clinical Immunology. in Practice
|January 2, 2019
Summary
Adult-onset atopic dermatitis (AD) affects one in four adults and presents differently than childhood AD. Early diagnosis and management are crucial, considering differential diagnoses like allergic contact dermatitis.
Area of Science:
- Dermatology
- Immunology
Background:
- Atopic dermatitis (AD) frequently presents in adulthood, accounting for 25% of adult cases.
- Adult-onset AD exhibits distinct phenotypic characteristics compared to childhood-onset AD.
- A comprehensive differential diagnosis is essential for new-onset eczematous eruptions in adults.
Purpose of the Study:
- To review the diagnostic approaches for adult-onset atopic dermatitis.
- To outline the recommended workup for suspected adult-onset AD.
- To discuss current management strategies for adult-onset atopic dermatitis.
Main Methods:
- Literature review focusing on adult-onset atopic dermatitis.
- Analysis of diagnostic criteria and differential diagnoses.
- Evaluation of management guidelines and treatment options.
Main Results:
- Adult-onset AD requires careful consideration of alternative diagnoses such as allergic contact dermatitis, mycosis fungoides, psoriasis, and scabies.
- Patch testing is recommended to exclude allergic contact dermatitis.
- Skin biopsy may be necessary to differentiate AD from other conditions like cutaneous T-cell lymphoma and psoriasis.
Conclusions:
- Adult-onset atopic dermatitis is a significant clinical entity requiring specific diagnostic considerations.
- Distinguishing adult-onset AD from other eczematous conditions is critical for appropriate patient care.
- Timely diagnosis and targeted management are key to improving outcomes for adults with new-onset AD.
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