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Updated: Jan 31, 2026

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
Published on: January 27, 2023
Explanatory models in neonatal intensive care: a tutorial.
Willem W L van Meurs1, Timothy A J Antonius2,3
11Cardiovascular and Respiratory Physiology Group, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands.
Explanatory models (EMs) offer an intuitive way to understand complex physiology for fragile patients. This educational technology aids clinical reasoning and communication, particularly in neonatal intensive care.
Area of Science:
- Medical Education
- Clinical Physiology
- Computational Medicine
Background:
- Acute care providers face challenges with complex patient physiology and information overload from traditional educational tools.
- Causal chain explanations have limitations in complex physiological systems.
- A new educational technology is introduced to simplify understanding and reasoning in clinical settings.
Purpose of the Study:
- To introduce a novel concept and educational technology for intuitive understanding of complex physiology.
- To facilitate clinical reasoning and communication among healthcare providers.
- To explore the utility of explanatory models in medical education.
Main Methods:
- Developed an explanatory model (EM) representing physiological processes, interventions, and pathologies.
- Adapted a conceptual model of the neonatal cardiorespiratory system for Transposition of the Great Arteries (TGA).
- Implemented the model in interactive, animated software for educational use.
Main Results:
- The software illustrates relationships between interventions and monitored variables in neonates with TGA.
- Learners can explore clinical scenarios and the effects of therapeutic interventions.
- The explanatory model provides insights into complex physiological interdependencies.
Conclusions:
- Explanatory models show potential as mental models for clinical practice.
- These models may aid clinical decision-making in neonatal intensive care and other fields.
- The developed educational technology offers a promising approach to complex physiological understanding.
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