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Myocardial Infarction and Functional Outcome Assessment in Pigs
Published on: April 25, 2014
[Analysis of pre-hospital delay time of patients with myocardial infarction]
András Jánosi1, Gábor Csató2, Ferenc Péter Pach3
1Gottsegen György Országos Kardiológiai Intézet Budapest, Haller u 29., 1096.
Insights
Reducing patient decision time and increasing primary transport for ST-elevation myocardial infarction (STEMI) patients can improve care. Faster interventions, like percutaneous coronary revascularization, are crucial for better outcomes in heart attack patients.
Area of Science:
- Cardiology
- Emergency Medicine
- Public Health
Background:
- Pre-hospital delay significantly impacts outcomes for ST-elevation myocardial infarction (STEMI) patients.
- Timely percutaneous coronary revascularization (PCI) is critical for restoring blood flow and minimizing myocardial damage.
- Understanding and optimizing the entire patient pathway, from symptom onset to reperfusion, is essential for improving STEMI management.
Purpose of the Study:
- To analyze pre-hospital delay in STEMI patients undergoing PCI.
- To compare care pathways and times for patients admitted directly to a cardiac catheterization facility versus those with secondary transport.
- To identify key factors influencing total ischemic time and inform strategies for improved patient outcomes.
Main Methods:
- Retrospective analysis of 7146 STEMI patients from the Hungarian Myocardial Infarction Registry (HUMIR) and National Ambulance Service (OMSZ) database (2014-2016).
- Investigation of pre-hospital time intervals: patient delay time (PDT), ambulance response (R1), on-scene time (R2), and transport time (R3).
- Comparison of total ischemic time (symptom onset to balloon inflation) between primary PCI centers (C) and non-PCI facilities with secondary transport (H).
Main Results:
- Patients primarily transported to a PCI-capable hospital (C) had a shorter median total ischemic time (260 minutes) compared to those with secondary transport (H) (356 minutes).
- Median patient delay time (PDT) was similar between groups (114 min for C, 121 min for H).
- While ambulance response and on-scene times (R1, R2) were comparable, transport time to the center (R3) was longer for group C.
Conclusions:
- Improving STEMI care requires reducing patient decision time (PDT) and increasing the proportion of primary PCI transports.
- Current ambulance response and on-scene care times (R1, R2) are acceptable, but further analysis of transport times (R3) may be beneficial.
- Optimizing the pre-hospital pathway and reducing delays are crucial for minimizing ischemic time and improving outcomes for STEMI patients.
Introduction And Aim:
The authors examined the pre-hospital delay of patients with ST-elevation myocardial infarction receiving percutaneous coronary revascularization.
Method:
In the Hungarian Myocardial Infarction Registry (HUMIR), between January 1, 2014 and March 31, 2016, 7146 patients were found who had all necessary time intervals available. In the database of the National Ambulance Service (OMSZ), 3288 patients were found who had the necessary time intervals. The following time intervals were investigated: the time from the beginning of the complaint to the rescue service notification (patient delay time = PDT), the time of the rescue service to arrive at the scene (R1), the on-site care time (R2) and the time from the scene until arriving to the centre (R3). The case of care at the centre, we investigated the time from the onset of symptoms until the balloon inflation (SBI). If the first hospital had no cardiac catheterization laboratory, we measured the transfer time to the cath centre. The methodological details related to the operation of the HUMIR had been described in our earlier communication. Rescue times (R1, R2, R3) were investigated on the basis of the paper-based records of the National Emergency Service. The patients were divided into two groups based on the fact that the first admission hospital is a centre with a heart catheter facility (C) or a non-invasive hospital (H).
Results:
2621 patients (79.7%) were admitted to a hospital with cath lab (C) and 667 patients with secondary transport. Patients with primary transport to C were younger, but for other data, the two groups did not differ. The median of PDT for patients in group C was 114, and 121 minutes for patients in group H. There was no significant difference between R1 and R2 time between the two groups. R3 time in group C was longer than for H patients. In the case of secondary transport, the median time was 98 minutes until the centre. The median time from the beginning of the complaint to the balloon inflation (total ischemic time) was 260 minutes in group C and 356 minutes in group H.
Conclusion:
Based on the analysis of the total ischemic time and the pre-hospital delay, it is clear that the care of myocardial infarction patients can be further improved by reducing the patient's decision time and increasing the proportion of primary transport. Rescue times (R1, R2, R3) met the expectations, however, further analysis of the M2 time should be considered. Orv Hetil. 2019; 160(1): 20-25.
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