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Updated: Jan 31, 2026

Cellular Affinity of Particle-Stabilized Emulsion to Boost Antigen Internalization
Published on: September 2, 2022
Self-assembling GO/modified HEC hybrid stabilized pickering emulsions and template polymerization for biomedical
Xiangdong Wang1, Kexin Yu1, Ran An1
1College of Polymer Science and Engineering, Sichuan University, Chengdu 610065, China.
Abstract:
Graphene oxide(GO), as an amphiphilic and biocompatible material, is often used to prepare Pickering emulsion. However, the preparation of stable Pickering emulsion by a low concentration of GO is very challenging. In this research, we prepared the hydrophobic modified hydroxyethyl cellulose (mHEC) which contained quaternary ammonium group and GO which the water contact angle was 84°-86°. A stable, low cost, and biocompatible Pickering emulsion was fabricated by a low concentration of GO and different contents of mHEC. The effects of mHEC concentration, electrolyte concentration, pH, and oil/water ratio on the stability of Pickering emulsion were investigated. What's more, we prepared the biomedical macroporous polyacrylamide hydrogel by the GO/mHEC composite stabilized emulsion template for drug controlled-release. The composite hydrogel by Pickering emulsion template is a potential drug controlled-release delivery platforms. Furthermore, our strategy is extremely versatile, as Pickering particles, polymer and the monomer of hydrogel can all be varied.
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