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Updated: Jan 31, 2026
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Quantitation of Protein Expression and Co-localization Using Multiplexed Immuno-histochemical Staining and Multispectral Imaging
Published on: April 8, 2016
13.4K
Quantitative cosmetic evaluation of long-lasting foundation using multispectral imaging.
Takashi Nagaoka1, Yuichi Kimura1
1Department of Computational Systems Biology, Faculty of Biology-Oriented Science and Technology, Kindai University, Kinokawa, Japan.
Summary
This study introduces a hyperspectral imager (HSI) to quantitatively assess long-lasting foundation on skin. The HSI system effectively measures foundation application state using reflectance standard deviation at 800 nm.
Area of Science:
- Cosmetic Science
- Biomedical Optics
- Imaging Technology
Background:
- Quantitative evaluation of cosmetic product performance is crucial.
- Hyperspectral imaging (HSI) offers simultaneous spatial and spectral data acquisition.
- Assessing long-lasting foundation efficacy requires objective measurement methods.
Purpose of the Study:
- To identify optimal wavelengths for quantitatively evaluating long-lasting foundation using HSI.
- To develop a non-invasive method for assessing cosmetic application state over time.
Main Methods:
- A reputable long-lasting foundation was applied to 10 healthy volunteers.
- Skin measurements were performed using a newly developed HSI system every 2 hours for 6 hours.
- The application state of the foundation was quantified using the standard deviation of reflectance.
Main Results:
- A strong correlation was found between standard deviation of reflectance and foundation application state across multiple wavelengths.
- The 800 nm wavelength demonstrated a reliable quantitative evaluation of foundation application, independent of subject oxygen saturation.
- HSI provides a robust method for tracking cosmetic wear over time.
Conclusions:
- The developed HSI system enables quantitative assessment of cosmetic-applied skin.
- This technology is expected to improve the efficiency of volunteer experiments for cosmetic product testing.
- Objective, wavelength-specific measurements can enhance cosmetic efficacy evaluation.
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