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Updated: Jan 31, 2026
![The Synthesis of [Sn10SiSiMe334]2- Using a Metastable SnI Halide Solution Synthesized via a Co-condensation Technique](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F54498.jpg&w=3840&q=50)
The Synthesis of [Sn10SiSiMe334]2- Using a Metastable SnI Halide Solution Synthesized via a Co-condensation Technique
Published on: November 28, 2016
Novel Aminomethyl Derivatives of 4-Methyl-2-prenylphenol: Synthesis and Antioxidant Properties
Evgeny V Buravlev1, Irina V Fedorova1, Oksana G Shevchenko2
1Institute of Chemistry, Komi Scientific Centre, Ural Branch of the Russian Academy of Sciences, 48, Pervomayskaya St., 167000, Syktyvkar, Komi Republic, Russian Federation.
Abstract:
4-Methyl-2-prenylphenol (1) was synthesized from para-cresol and prenol, natural alcohol under the conditions of heterogeneous catalysis. A series of nine new aminomethyl derivatives with secondary and tertiary amino groups were obtained on the basis of compound 1. A comparative evaluation of their antioxidant properties was carried out using in vitro models. It was established that Mannich base with octylaminomethyl group has radical-scavenging activity, high Fe2+ -chelation ability as well as the ability to inhibit oxidative hemolysis of red blood cells.
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