Related Experiment Video
Updated: Jan 31, 2026

Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis
Published on: June 30, 2023
Construct validity of acute morbidity as a novel outcome for emergency patients
Fabrizia Schmid1, Alexandra Malinovska2, Karin Weigel3
1Emergency Department, University Hospital Basel, Basel, Switzerland.
Objectives:
Validation of acute morbidity as a novel outcome in emergency medicine.
Methods:
Construct validity of acute morbidity was established by comparison to other outcomes using linear and logistic regression models.
Results:
Data of 4608 patients were analysed. 1869 patients (40.6%) fulfilled the criteria for acute morbidity. Using multivariate analyses, acute morbidity was associated with outcomes such as hospitalisation (OR: 11, 95%-CI 9-13), mortality (OR 15, 95%-CI 6-49), and ICU admission (OR: 46, 95%-CI 25-96). Reliability of the construct "acute morbidity" was estimated using Cohens Kappa, which was 0.96 for intra-rater and 0.94 for inter-rater reliability.
Conclusion:
Reliability of the framework for acute morbidity was high. Construct validity was shown by associations with hospitalisation, mortality, and ICU admission.
Related Concept Videos
Reliability and Validity
Emerging Adulthood
Predicting Reaction Outcomes
Outcomes of Glycolysis
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
Introduction Cardiac Emergencies
Data Validation
Key parameters for method validation include:

